Researchers evaluate new cleansing methods in the wake of Phospho-soda recall
Researchers are investigating new methods for pre-colonoscopy bowel cleansing following the recall of Fleet’s Phospho-soda products. The C.B. Fleet Company recalled the oral sodium phosphate solutions “Fleet Phospho-soda” and “Fleet Phospho-soda EZ-Prep Bowel Cleansing System” in December 2008 after they were linked to a form of permanent kidney damage.
Scientists at an annual meeting of the American College of Gastroenterology presented several studies analyzing new methods for bowel preparation. A study comparing the use of polyethelne glycol plus ascorbic acid (Moviprep) compared to magnesium citrate found that both methods were safe and effective for pre-colonoscopy bowel cleansing.
In a second study, researchers evaluated the effectiveness of a new oral sulfate solution (Suprep) compared to a polyethylene glycol and electrolytes solution (NuLytely) for cleansing the proximal—or right—colon. The study found that the oral sulfate solution was the more effective of the two products studied.
Fleet recalled its Phospho-soda solutions after the Food and Drug Administration warned that they could increase the risk of a type of kidney failure known as acute phosphate nephropathy. This condition occurs when calcium-phosphate crystals collect inside the kidneys, leading to acute renal failure. Patients who develop acute phosphate nephropathy may suffer permanent kidney damage and may need to undergo kidney transplant surgery.